Perturbing Thermodynamically Unfeasible Metabolic Networks
نویسندگان
چکیده
Reactions within the cell should satisfy the law of mass conservation and the second law of thermodynamics. Networks of reactions violating any of these laws are unphysical and cannot occur in nature. In this paper we describe a technique that perturbs an unfeasible network to produce a metabolic network that satisfies the two fundamental laws. This algorithm has been applied to study the metabolic pathways of E. coli. IV BSB 11 Favor ver os Anais do Simpósio em Springer Verlag, Lecture Notes in Bioinformatics (LNBI número 3594) para este trabalho. Please see the Symposium Proceedings in Lecture Notes in Bioinformatics (LNBI nr. 3594), Springer Verlag, for this paper.
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